In Tokyo, a weak, unassertive boy named Sena Kobayakawa enters the high school of his choice, Deimon Private Senior High School. Sena's only remarkable physical abilities are his running speed and agility, which are noted by the school's American football team captain Yoichi Hiruma. Hiruma forces Sena to join the Deimon Devil Bats football team as its running back. To protect his identity from other teams who want to recruit him, Sena is forced to publicly assume the role of the team secretary and enter the field under the pseudonym of "Eyeshield 21" wearing a helmet with an eyeshield to hide his features.
Sena Kobayakawa / Eyeshield 21 (voice)
Yoichi Hiruma
Mamori Anezaki
Haruto Sakuraba
Raimon Tarou
Ryokan Kurita
Hayato Akaba
Kengo Mizumachi
Devil Bat
Niinobu Kasamatsu
Naosumi Kadoguchi
Osamu Kobanzame
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